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Contatti

La Prof.ssa Nicoletta Di Simone riceve a Roma e Milano su appuntamento.

Informazioni di Contatto

PUBBLICAZIONI

Syncytiotrophoblast-derived extracellular vesicles carry apolipoprotein-E and affect lipid synthesis of liver cells in vitro. Chiara Tersigni, Muhammad Furqan Bari, Shijei Cai,  Wei Zhang, Neva Kandzija,  Alice Buchan,  Fabrizio Miranda, Nicoletta Di Simone, Christopher W Redman, Claire Bastie, Manu Vatish. J Cell Mol Med, 2022 Jan;26(1):123-132. doi: 10.1111/jcmm.17056. Epub 2021 Dec 10. 

α-Lipoic Acid and its Role on Female Reproduction. Fiorella Di Nicuolo, Roberta Castellani, Carlo Ticconi, Giovanni ScambiaAlfredo Pontecorvi,  Nicoletta Di SimoneCurr Protein Pept Sci,2021 Dec 29;22(11):767-774. doi: 10.2174/1389203722666211029102417.

Glucose/insulin metabolism and vitamin D in women with recurrent pregnancy loss. Silvia D'Ippolito,  Anna Capozzi, Giovanni Scambia, Roberto Sorge, Stefano Lello,  Nicoletta Di SimoneAm J Reprod Immunol, 2022 Jan;87(1):e13505. doi: 10.1111/aji.13505. Epub 2021 Nov 10.

CD93 a potential player in cytotrophoblast and endothelial cell migration. Sonia Fantone, Giovanni Tossetta, Nicoletta Di Simone, Chiara Tersigni, Giovanni Scambia, Fabio Marcheggiani,  Stefano R GiannubiloDaniela Marzioni. Cell Tissue Res, 2022 Jan;387(1):123-130. doi: 10.1007/s00441-021-03543-3. Epub 2021 Oct 21.

Circulating Placental Vesicles Carry HLA-DR in Pre-Eclampsia: A New Potential Marker of the Syndrome. Chiara Tersigni, Donatella Lucchetti,  Rita Franco,  Filomena Colella, Caterina Neri,  Laura Crispino, Alessandro Sgambato,  Antonio Lanzone, Giovanni Scambia, Manu Vatish, Nicoletta Di Simone.Front Immunol, 2021 Sep 3;12:717879. doi: 10.3389/fimmu.2021.717879. eCollection 2021.

Editorial: Immunological Role of the Maternal Microbiome in Pregnancy. Nicoletta Di Simone, Eytan Robert Barnea,  Martin Mueller. Front. Immunol, 2021 Jun 21;12:703009. doi: 10.3389/fimmu.2021.703009.eCollection 2021.

Clinical consequences of defective decidualization. Carlo Ticconi,  Nicoletta Di Simone,  Luisa Campagnolo,  Asgerally Fazleabas. Tissue Cell, 2021 Oct;72:101586. doi: 10.1016/j.tice.2021.101586. Epub 2021 Jun 25.

Alpha-Lipoic Acid Plays a Role in Endometriosis: New Evidence on Inflammasome-Mediated Interleukin Production, Cellular Adhesion and Invasion. Fiorella Di Nicuolo, Roberta Castellani, Alessandra De Cicco Nardone,  Greta Barbaro, Carmela Paciullo, Alfredo Pontecorvi,  Giovanni Scambia, Nicoletta Di SimoneMolecules, 2021 Jan 8;26(2):288. doi: 10.3390/molecules26020288.

Hysteroscopic removal of a gauze inadvertently retained in uterus for two years following caesarean section. Silvia Amodeo,  Nicoletta Di Simone, Vito Chiantera,  Giovanni Scambia, Valeria Masciullo. J Obestet Jinaecol. 2021 Apr;41(3):481-483. doi: 10.1080/01443615.2020.1828317. Epub 2021 Jan 11. 

[Advisory Board Italiano sulla sindrome dell'ovaio policistico (PCOS): dalle osservazioni all'esperienze cliniche sull'uso del mioinositolo (MYO) e dell'acido alfa-lipoico (ALA) per migliorare i quadri della sindromeFerrazzi E. M.,  Moghetti P., Fruzzetti F., Gambineri A., Fulghesu A. M.Street M. E.,  Rago R., Cetin I., Mandò C.,  Di Simone N., Genazzani A. D., Apa R.De Leo V. Minerva Ginecol. 2020 Oct;72(5):239-284.doi: 10.23736/S0026-4784.20.04575-X.

Recent Insights on the Maternal Microbiota: Impact on Pregnancy Outcomes. Di Simone N., Ortiz A. S., Specchia M.,  Tersigni C.,  P.,  Gasbarrini A.,  Giovanni Scambia G.,  D'Ippolito S. Front. Immunol. 2020 Oct 23;11:528202.doi: 10.3389/fimmu.2020.528202. eCollection 2020.

Impact of maternal obesity on the risk of preterm delivery: insights into pathogenic mechanisms. Tersigni C, Neri C, D'Ippolito S, Garofalo S, Martino C, Lanzone A, Scambia G, Di Simone N. J Matern Fetal Neonatal Med. 2020 Sep 17:1-6. doi: 10.1080/14767058.2020.1817370.

Pregnancy-Related Complications in Women with Recurrent Pregnancy Loss: A Prospective Cohort Study. Ticconi C, Pietropolli A, Specchia M, Nicastri E, Chiaramonte C, Piccione E, Scambia G, Di Simone N. J Clin Med. 2020 Sep 1;9(9):E2833.

Celiac disease and reproductive failures: An update on pathogenic mechanisms. Di Simone N, Gratta M, Castellani R, D'Ippolito S, Specchia M, Scambia G, Tersigni C. Am J Reprod Immunol. 2020 Aug 31:e13334.

Expression of Pinopodes in the Endometrium from Recurrent Pregnancy Loss Women. Role of Thrombomodulin and Ezrin. D'Ippolito S, Di Nicuolo F, Papi M, Castellani R, Palmieri V, Masciullo V, Arena V, Tersigni C, Bernabei M, Pontecorvi A, Scambia G, Di Simone N. J Clin Med. 2020 Aug 13;9(8):2634.

Pre-eclampsia predictive ability of maternal miR-125b: a clinical and experimental study. Licini C, Avellini C, Picchiassi E, Mensà E, Fantone S, Ramini D, Tersigni C, Tossetta G, Castellucci C, Tarquini F, Coata G, Giardina I, Ciavattini A, Scambia G, Di Renzo GC, Di Simone N, Gesuita R, Giannubilo SR, Olivieri F, Marzioni D. Transl Res. 2020 Jul 26:S1931-5244(20)30179-1. doi: 10.1016/j.trsl.2020.07.011.

Role of Human Leukocyte Antigens at the Feto-Maternal Interface in Normal and Pathological Pregnancy: An Update. Tersigni C, Meli F, Neri C, Iacoangeli A, Franco R, Lanzone A, Scambia G, Di Simone N. Int J Mol Sci. 2020 Jul 4;21(13):E4756 I.F. 4.556

Synthetic PreImplantation Factor (sPIF) reduces inflammation and prevents preterm birth. Spinelli M, Boucard C, Di Nicuolo F, Haesler V, Castellani R, Pontecorvi A, Scambia G, Granieri C, Barnea ER, Surbek D, Mueller M, Di Simone N. PLoS One. 2020 Jun 8;15(6):e0232493.  I.F. 2.870

CDT reference values for monitoring chronic alcohol abuse in pregnancy. Bortolotti F, Raffaelli R, Di Simone N, Semprebon M, Mirandola M, Simonetto C, De Marchi F, Trevisan MT, Carli G, Dorizzi RM, Scambia G, Franchi M, Tagliaro F. Clin Chim Acta. 2020 Apr 14;507:156-160. I.F 2.735

Recurrent miscarriage and fetal congenital malformations: Is there a neglected causal association? Visconti D, Neri C, De Santis M, Sabusco GP, Gratta M, Campagna G, Lanzone A, Scambia G, Di Simone N. Eur J Obstet Gynecol Reprod Biol. 2020 Mar 7;248:233-237. I.F 2.024

Time-to-Pregnancy in Women with Unexplained Recurrent Pregnancy Loss: A Controlled Study. Ticconi C, Pietropolli A, D'Ippolito S, Chiaramonte C, Piccione E, Scambia G, Di Simone N. Reprod Sci. 2020 May;27(5):1121-1128. I.F 2.559

Abnormal uterine inflammation in obstetric syndromes: molecular insights into the role of chemokine decoy receptor D6 and inflammasome NLRP3. Tersigni C, Vatish M, D'Ippolito S, Scambia G, Di Simone N. Mol Hum Reprod. 2020 Feb 29;26(2):111-121. I.F 3.396

Gut and Lung Microbiota in Preterm Infants: Immunological Modulation and Implication in Neonatal Outcomes. Tirone C, Pezza L, Paladini A, Tana M, Aurilia C, Lio A, D'Ippolito S, Tersigni C, Posteraro B, Sanguinetti M, Di Simone N, Vento G. Front Immunol. 2019 Dec 12;10:2910. I.F 4.716

Endometrial Immune Dysfunction in Recurrent Pregnancy Loss. Ticconi C, Pietropolli A, Di Simone N, Piccione E, Fazleabas A. Int J Mol Sci. 2019 Oct 26;20(21). I.F. 4.183

The pathogenic role of autoantibodies in recurrent pregnancy loss. D’Ippolito S, Ticconi C, Tersigni C, Garofalo S, Martino C, Lanzone A, Scambia G, Di Simone N. Am J Reprod Immunol. 2019 Oct 21:e13200. I.F. 3.091

Effect of alpha-lipoic acid and myoinositol on endometrial inflammasome from recurrent pregnancy loss women. Di Nicuolo F, D’Ippolito S, Castellani R, Rossi ED, Masciullo V, Specchia M, Mariani M, Pontecorvi A, Scambia G, Di Simone N. Am J Reprod Immunol. 2019 Sep;82(3):e13153. I.F. 3.091

Pre-eclampsia onset and SPARC: A possible involvement in placenta development. Tossetta G, Fantone S, Giannubilo SR, Marinelli Busilacchi E, Ciavattini A, Castellucci M, Di Simone N, Mattioli-Belmonte M, Marzioni D. J Cell Physiol. 2019 May;234(5):6091-6098. I.F. 4.522

Endometrial microbes and microbioma: recent insights on the inflammatory and immune players of the human endometrium. D’Ippolito S, Di Nicuolo F, Pontecorvi A, Gratta M, Scambia G, Di Simone N. Am. J. Reprod. Immunol. 2018 Dec; 80(6): e13065. I.F. 3.091

Pre-eclampsia onset and SPARC: a possible involvment in placenta development. Tossetta G, Fantone S, Giannubilo SR, Marinelli Busilacchi E, Ciavattini A, Castellucci M, Di Simone N, Mattioli-Belmonte M, Marzioni D. J Cell Physiol 2019; May; 234(5): 6091-6098. I.F. 3.923

HLA-DR is aberrantly expressed at feto-maternal interface in pre-eclampsia. Tersigni C, Redman CW, Dragovich R, Tannetta D, Scambia G, Di Simone N, Sargent I, Vatish M. J. Reprod Immunol 2018; Sept; 129:48-52. I.F. 2.654

An emerging role of endometrial inflammosome in reproduction: new therapeutic approaches. Di Nicuolo F, Specchia M, Trentavizi L, Pontecorvi A, Scambia G, Di Simone N. Protein Pept Lett 2018; 25(5):455-462
IF 1.168

Recurrent pregnancy loss is associated to leaky gut: a novel pathogenic model of endometrium inflammation? Tersigni C, D’Ippolito S, Valenza V, Di Nicuolo F, Marana R, Masciullo V, Scaldaferri F, Malatacca F, de Waure C, Gasbarrini A, Scambia G, Di Simone N. J Trans. Med 2018; Apr 17;16 (1): 102. I.F. 4.098

The chromosome analysis of the miscarriage tissue. Miscarried embryo/fetal crown rump length (CRL) measurement: a practical use. D’Ippolito S, Di Simone N, Orteschi D, Pomponi MG, Genuardi M, Sisti LG, Castellani R, Rossi ED, Scambia G, Zollino M. 2017 PLoS One 2017, Jun 12;12(6):e0178113. I.F 2.776

Synthetic pre-implantation factor (PIF) prevents fetal loss by modulating LPS induced inflammatory response. Di Simone N, Di Nicuolo F, Marana R, Castellani R, Ria F, Veglia M, Scambia G, Surbek D, Mueller, M, Barnea, ER. PLOS One 2017 Jul 12; 12(7):e0180642. I.F. 2.776

Placental Chemokine Receptor D6 is Functionally Impaired in Pre-eclampsia. Tersigni C, Di Nicuolo F, Maulucci G, Rolfo R, Giuffrida D, Veglia M, De Spirito M, Scambia G, Todros T, Di Simone N. PLoS One. 2016 Oct 25;11(10):e0164747. I.F. 2.776

Antinuclear autoantibodies and pregnancy outcome in women with unexplained recurrent miscarriage. Ticconi C, Pietropolli A, Borelli B, Bruno V, Piccione E, Bernardini S, Di Simone N. Am J Reprod Immunol. 2016 Sep 12. I.F. 3.091

Helicobacter pylori infection contributes to placental impairment in preeclampsia: basic and clinical evidencesDi Simone N, Tersigni C, Cardaropoli S, Franceschi F, Di Nicuolo F, Castellani R, Bugli F, de Waure C, Cavaliere AF, Gasbarrini A, Sanguinetti M, Scambia G, Todros T. Helicobacter. 2016 Aug 3. I.F. 3.352

Human leukocyte antigen (HLA) DQ2/DQ8 prevalence in recurrent pregnancy loss women. D’ Ippolito S, Gasbarrini A, Castellani R, Rocchetti S, Sisti LG, Scambia G, Di Simone N. Autoimmun Rev 2016; 13: S1568-S9972. I.F. 7.716

Inflammosome in the human endometrium:further step in the evaluation of the “maternal side”. D’Ippolito S, Tersigni C, Marana R, Di Nicuolo F, Gaglione R, Rossi ED, Castellani R, Scambia G, Di Simone N. Fertil Steril 2016 Jan;105(1):111-118.e4. I.F. 5.411

Non-hormonal treatment of vulvo-vaginal atrophy-related syntoms in post-menopausal women. Tersigni C, Di Simone N, Tempestilli E, Cinfrini F, Russo S, Moruzzi MC, Amar ID, Fiorelli A, Scambia G, Villa P. J Obstet Gynaecol. 2015 May 13:1-4. I.F. 0.588

Human IgG Antinuclear Antibodies Induce Pregnancy Loss in Mice by Increasing Immune Complex Deposition in Placental Tissue: In Vivo Study. Veglia M, D’Ippolito S, Marana R, Di Nicuolo F, Castellani R, Bruno V, Fiorelli A, Ria F, Maulucci G, De Spirito M, Migliara G, Scambia G, Di Simone N. Am J Reprod Immunol 2015;Dec;74(6):542-52. I.F. 3.091

Insights into the Role of Helicobacter pylori Infection in Preeclampsia: From the Bench to the Bedside. Tersigni C, Franceschi F, Todros T, Cardaropoli S, Scambia G, Di Simone N. Front Immunol. 2014 Oct 9;5:484. I.F. 4.716

Obstetric Antiphospholipid syndrome: A recent classification for an old defined disorder. D’Ippolito S, Meroni PL, Koike T, Veglia M, Scambia G, Di Simone N. Autoimmun Rev. 2014;13(9):901-908. I.F. 7.716

Celiac disease and reproductive disorders: meta-analysis of epidemiologic associations and potential pathogenic mechanisms. Tersigni C, Castellani R, de Waure C, Fattorossi A, De Spirito M, Gasbarrini A, Scambia G, Di Simone N. Hum Reprod Update 2014;20(4):582-93. I.F.12.878

Potential new mechanisms of placental damage in celiac disease: Anti-tranglutaminase antibodies impair human endometrial angiogenesis. Di Simone N, De Spirito M, Di Nicuolo F, Tersigni C, Castellani R, Silano M, Maulucci G, Papi M, Scambia G, Gasbarrini A. Biol Reprod. 2013;89(4):88. I.F. 2.960

Antiphospholipid Antibodies Affect Human Endometrial Angiogenesis: Protective Effect of a Synthetic Peptide (TIFI) Mimicking the Phospholipid Binding Site of β2 glycoprotein I. Di Simone N, D’Ippolito S, Marana R, Di Nicuolo F, Castellani R, Pierangeli SS, Chen P, Tersigni C, Scambia G, Meroni PL. Am J Reprod Immunol. 2013;70(4):299-308. I.F. 3.091

Emerging nonanticoagulant role of low molecular weight heparins on extravillous trophoblast functions and on heparin binding-epidermal growth factor and cystein-rich angiogenic inducer 61 expression. D’Ippolito S, Di Nicuolo F, Marana R, Castellani R, Stinson J, Tersigni C, Scambia G, Di Simone N. Fertil Steril. 2012 Oct; 98 (4):1028-36. I.F. 5.411

Effect of pravastatin on endothelial function and endothelial progenitor cells in healthy postmenopausal women. Paradisi G, Bracaglia M, Basile F, D’Ippolito S, Di Nicuolo F, Ianniello F, Quagliozzi L, Donati L, Labianca A, Di Cesare C, Viggiano M, Biaggi A, De Waure C, Andreotti F, Di Simone N, Caruso A. Clin Exp Obstet Gynecol. 2012;39(2):153-9.

Antibodies anti-CagA cross-react with trophoblast cells: a risk factor for pre-eclampsia? Franceschi F, Di Simone N, D’Ippolito S, Castellani R, Di Nicuolo F, Gasbarrini G, Yamaoka Y, Todros T, Scambia G, Gasbarrini A. Helicobacter. 2012;17(6):426-34. I.F. 3.352

Alterations of maternal plasma HTRA1 level in preeclampsia complicated by IUGR. Marzioni D, Lorenzi T, Altobelli E, Giannubilo SR, Paolinelli F, Tersigni C, Crescimanno C, Monsurrò V, Tranquilli AL, Di Simone N, Castellucci M. Placenta. 2012;33(12):1036-8. I.F. 2.773

Adipokines, an adipose tissue and placental product with biological functions during pregnancy. D’Ippolito S, Tersigni C, Scambia G, Di Simone N. Biofactors 2012;38(1):14-23. I.F. 3.598

In vitro evidences of heparin’s effects on embryo implantation and trophoblast development. Tersigni C, Marana R, Santamarìa A, Castellani R, Scambia G, Di Simone N. Reprod Sci. 2012;19(5):454-62. I.F. 2.559

Effect of Low Molecular Weight Heparins (LMWHs) on antiphospholipid Antibodies (aPL) – Mediated Inhibition of Endometrial Angiogenesis. D’Ippolito S, Marana R, Di Nicuolo F, Castellani R, Veglia M, Stinson J, Scambia G, Di Simone N. PloS One. 2012;7 (1): e29660. I.F. 2.776

Low-molecular-weight heparins induce decidual heparin-binding epidermal growth factor-like growth factor expression and promote survival of decidual cells undergoing apoptosis. Di Simone N, Di Nicuolo F, Castellani R, Veglia M, Tersigni C, Silano M, Tritarelli A, Scambia G, Marana R. Fertil Steril. 2012;97(1):169-177. I.F. 5.411

Anti-phospholipid induced murine fetal loss: Novel protective effect of a peptide targeting the β2 glycoprotein I phospholipid-binding site. Implications for human fetal loss. Martinez de la Torre Y, Pregnolato F, D’Amelio F, Grossi C, Di Simone N, Pasqualini F, Nebuloni M, Chen P, Pierangeli S, Bassani N, Ambrogi F, Borghi MO, Vecchi A, Locati M, Meroni PL. J Autoimmun. 2012;38(2-3):J209-15. I.F. 7.543

Thyroid autoimmunity and recurrent miscarriage. Ticconi C, Giuliani E, Veglia M, Pietropolli A, Piccione E, Di Simone N. Am J Reprod Immunol. 2011;66(6):452-9. I.F. 3.091

Low Molecular Weight Heparin in obstetric care. A review of the literature. D’Ippolito S, Santamaria A, Veglia M, Tersigni C, Di Simone N. Reprod Sci. 2011;18(7):602-13. I.F. 2.559

New emerging roles of adipokines in fertility and reproduction. Tersigni C, Di Nicuolo F, D’Ippolito S, Veglia M, Castellucci M, Di Simone N. Obstet Gynecol Surv. 2011;66(1):47-63. I.F. 2.113

Low neonatal birth weight as a possible predictive factor for the onset of pastpartum eclampsia. Tersigni C, Esposito G, Albanese A, D’Ippolito S, Sabatino G, Di Simone N, Caruso A. Hypertens Pregnancy 2011;30(2):203-7. I.F. 1.736

Anti-tissue transglutaminase antibodies from celiac patients are responsible for trophoblast damage via apoptosis in vitro. Di Simone N, Silano M, Castellani R, Di Nicuolo F, D’Alessio MC, Franceschi F, Tritarelli A, Leone AM, Tersigni C, Gasbarrini G, Gentiloni Silveri N, Caruso A, Gasbarrini A. Am J Gastroenterology 2010;105(10):2254-61. I.F. 10.241

No evidence for fetal microchimerism in the skin of patients with pemphigoid gestationis. D’Alessio MC, Mazzanti C, Di Simone N, Mancuso S, Reddiconto G, Garzia M, Leone G, Gobello T, Caruso A. Eur J Dermatol 2010;20(1):122-3. I.F. 3.094

Antinuclear Autoantibodies in Women with Recurrent Pregnancy Loss. Ticconi C, Rotondi F, Veglia M, Pietropolli A, Bernardini S, Ria F, Caruso A, Di Simone N. Am J Reprod Immunol 2010;64(6):384-92. I.F. 3.091

Anti-phospholipid antibody mediated fetal loss: still an open question from a pathogenic point of view. Review. Meroni PL, Tedesco F, Locati M, Vecchi A, Di Simone N, Acaia B, Pierangeli SS, Borghi MO. Lupus. 2010;19(4):453-6. I.F. 2.924

Antiphospholipid Antibodies Affect Human Endometrial Angiogenesis. Di Simone N, Di Nicuolo F, D’Ippolito S, Castellani R, Tersigni C, Caruso A, Meroni P, Marana R. Biol Reprod 2010;83(2):212-9. I.F. 2.960

Decreased expression of heparin-binding epidermal growth factor-like growth factor as a newly identified pathogenic mechanism of antiphospholipid-mediated defective placentation. Di Simone N, Marana R, Castellani R, Di Nicuolo F, D’Alessio MC, Raschi E, Borghi MO, Chen PP, Sanguinetti M, Caruso A, Meroni PL. Arthritis Rheum. 2010;62(5):1504-12. I.F. 7.873

Resistin modulates glucose uptake and glucose transporter-1 (GLUT-1) expression in trophoblast cells. Di Simone N, Di Nicuolo F, Marzioni D, Castellucci M, Sanguinetti M, D’Ippolito S, Caruso A. J Cell Mol Med. 2009;13(2):388-97. I.F. 4.658

Antiphospholipid antibodies: effects on trophoblast and endothelial cells. D’Ippolito S, Di Simone N, Di Nicuolo F, Castellani R, Caruso A. Am J Reprod Immunol. 2007 Aug;58(2):150-8. Review. I.F. 3.091

Pregnancies complicated with antiphospholipid syndrome: the pathogenic mechanism of antiphospholipid antibodies: a review of the literatureDi Simone N, Luigi MP, Marco D, Fiorella DN, Silvia D, Clara DM, Alessandro C. Ann N Y Acad Sci. 2007 Jun;1108:505-14. Review. I.F. 4.295

Effects of antiretroviral therapy on tube-like network formation of human endothelial cellsDi Simone N, De Santis M, Tamburrini E, Di Nicuolo F, Lucia MB, Riccardi P, D’Ippolito S, Cauda R, Caruso A. Biol Pharm Bull. 2007 May;30(5):982-4. I.F. 1.540

Low-molecular weight heparin induces in vitro trophoblast invasiveness: role of matrix metalloproteinases and tissue inhibitorsDi Simone N, Di Nicuolo F, Sanguinetti M, Ferrazzani S, D’Alessio MC, Castellani R, Bompiani A, Caruso A.
Placenta. 2007 Apr;28(4):298-304. I.F. 2.773

Pathogenic role of anti-beta2-glycoprotein I antibodies on human placenta: functional effects related to implantation and roles of heparinDi Simone N, Meroni PL, D’Asta M, Di Nicuolo F, D’Alessio MC, Caruso A. Hum Reprod Update. 2007 Mar-Apr;13(2):189-96. I.F.12.878

Anti-beta2 glycoprotein I antibodies affect Bcl-2 and Bax trophoblast expression but without evidence of DNA fragmentation. Di Simone N, Castellani R, Raschi E, Meroni PL, Caruso Ann N Y Acad Sci 2006;1069:364-76. I.F. 4.295

Resistin regulates BeWo cells invasive behaviour and endothelial cells angiogenic processes. Di Simone N, Di Nicuolo F, Sanguinetti M, Castellani R, D’Asta M, Caforio L, Caruso A. J Endocrinol 2006;189(3):691-9. I.F. 4.381

Non-invasive detection of fetal Rhesus D status: a comparison between polymerase chain reaction and flow cytometry. Di Simone N, Lai M, Rumi C, Riccardi P, D’Asta M, Leone G, Mancuso S, Caruso A. Fetal Diagn Therap 2006; 21(5):404-9. I.F. 2.040

Pathogenic role of anti-ß2 glycoprotein I antibodies in antiphospholipid-associated fetal loss:characterization of ß2 glycoprotein I binding to trophoblast cells and functional effects of anti-ß2 glycoprotein I antibodies in vitro. Di Simone N, Raschi E, Testoni C, Castellani R, D’Asta M, Shi T, Krilis SA, Caruso A, Meroni PL. Ann Rheum Dis 2005;64:462-67. I.F. 14.299

Antiphospholipid antibodies as cause of pregnancy loss. Meroni PL, Di Simone N, Testoni C, D’Asta M, Acaia B, Caruso A. Lupus 2004;13:649-52. I.F. 2.924

Effect of folic acid on homocysteine-induced trophoblast apoptosis. Di Simone N, Riccardi P, Maggiano N, Piacentani A, D’Asta M, Capelli A, Caruso A. Mol Hum Reprod 2004;10:665-9. I.F. 3.396

Prostaglandin: cervical ripening in hypertensive pregnancies. Ferrazzani S. De Santis L, Carducci B, Calandro D, De Carolis S, Di Simone N, Caruso A. Acta Obstet Gynecol Scand 2003;82:510-5.
I.F. 2.741

Homocysteine induces trophoblast cell death with apoptotic features. Di Simone N, Maggiano N, Caliandro D, Riccardi P, Evangelista A, Carducci B, Caruso A. Biol Reprod 2003;69:1129-34.
I.F. 2.960

Regulation of endometrial adenocarcinoma cell proliferation by activin and its modulation by 17b-estradiol. Di Simone N, Schneyer AL, Caliandro D, Castellani R, Caruso A. Mol Cell Endocrinol. 2002;192:187-95.
I.F. 3.693

Antiphospholipid antibodies regulate the expression of trophoblast cell adhesion molecules. Di Simone N, Castellani R, Caliandro D, Caruso A. Fertil Steril. 2002;77:805-11.
I.F. 5.411

Monoclonal anti-annexin V antibody inhibits trophoblast gonadotrophin secretion and induces syncytiotrophoblast apoptosis. Di Simone N, Castellani R, Caliandro D, Caruso A. Biol Reprod. 2001; 65:1766-70.
I.F. 2.960

Interleukin-3 and human trophoblast: in vitro explanations for the effect of interleukin in antiphospholipid antibodies syndrome. Di Simone N, Caliandro D, Castellani R, Ferrazzani S, Caruso A. Fertil Steril. 2000;73:1194-1200.
I.F. 5.411

Antiphospholipid antibodies affect trophoblast gonadotrophin secretion and invasiveness by binding direclty and through adhered b2-glycoprotein 1. Di Simone N, Meroni PL, Del Papa N, Raschi E, Caliandro D, De Carolis S, Khamastha MA, Atsumi T, Hughes GRV, Balestrieri G, Tincani A, Casali P, Caruso A. Arth Rheum. 2000;43:140-50.
I.F. 6.787

Antiphospholipid antibodies in obstetrics: new complexities and sites of action. Caruso A, De Carolis S, Di Simone N. Hum Reprod Update.1999;5:267-76.
I.F. 12.878

Low-molecular weight heparin restores in vitro trophoblast invasiveness and differentiation in presence of immunoglobulin G fractions obtained from patients with antiphospholipid syndrome. Di Simone N, Caliandro D, Castellani R, Ferrazzani S, De Carolis S, Caruso A. Hum Reprod. 1999;14:489-95.
I.F. 5.506

Activin regulates ba-subunit and activin receptors mRNA and cellular proliferation in activin responsive testicular tumor (TT) cell. Di Simone N, Hall AH, Welt C, Schneyer AL. Endocrinology. 1998;129:1147-55.
I.F. 3.800

Heparin and low-dose aspirin restore placental hCG secretion abolished by antiphospholipd antibodies-containing sera. Di Simone N, Ferrazzani S, Castellani R, De Carolis S, Mancuso S, Caruso A. Hum Reprod.1997;12:2061-5.
I.F. 5.506

Insulin-like growth factor (IGF)-I and IGF-II stimulate progesterone production by human luteal cells: role of IGF-I as mediator of growth hormone action. Apa R, Di Simone N, Ronsisvalle E, Miceli F, De Feo D, Caruso A, Lanzone A, Mancuso S. Fertil Steril. 1996;66:235-9.
I.F. 5.411

Characterization of inhibin/activin subunit, folliststin and activin type II receptors in human ovarian cancer cell lines: a potential role in autocrine growth regulation. Di Simone N, Crowley WF, Wang QF, Schneyer AL. Endocrinology. 1996;137:486-94.
I.F. 3.800

Insulin plasma levels in pregnant patients with impaired glucose tolerance: relationship with pregnancy outcome. Di Simone N, Ronsisvalle E, Fulghesu AM, Lanzone A, Caruso A. Gynecol Obstet Invest. 1996;42:16-20.
I.F. 1.302

In vitro effect of antiphospholipid antibody-containing sera on basal and gonadotrophin-releasing hormone-dependent human chorionic gonadotrophin release by cultured cells. Di Simone N, De Carolis S, Lanzone A, Ronsisvalle E, Giannice R, Caruso A. Placenta. 1995;16:75-83.
I.F. 2.773

Polycystic ovary disease: a risk factor for gestational diabetes? Lanzone A, Caruso A, Di Simone N, De Carolis S, Fulghesu AM, Mancuso S. J Reprod Med. 1995;40:312-6.
I.F. 0.307

In vitro human growth hormone increases human chorionic gonadotropin and progesterone secretion by human placenta at term: evidence of a modulatory effect of opioids. Di Simone N, Caruso A, Lanzone A, Piccirillo G, Castellani R, Ronsisvalle E, Giannice R, Mancuso S. Gynecol Endocrinol. 1995;9:1-8.
I.F. 1.406

Insulin secretion in gestational diabetes patients: a relationship with outcome of the pregnancy. Caruso A, Di Simone N, Ronsisvalle E, Lanzone A, Mancuso S. Horm Res. 1994; 41:205-8.
I.F 2.423

Effect of activin-A on progesterone synthesis in human luteal cells. Di Simone N, Lanzone A, Petraglia F, Ronsisvalle E, Caruso A, Mancuso S. Fertil Steril, 1994;62:1157-61.
I.F. 5.411

Human growth hormone enhances progesterone production by luteal cells in vitro. II Evidence of a distinct effect on two luteal cell types. Di Simone N, Castellani R, Lanzone A, Caruso A, Mancuso S. Fertil Steril. 1993;60:47-52.
I.F 5.411

Beta-hydroxybutyrate is a biological marker of insulin deficiency in gestational diabetes. Caruso A, Di Simone N, Lanzone A, Riccardi P, Piccirillo G, Ronsisvalle E, Mancuso S. It J Obstet Gynecol. 1993:11-15.
IF 0.545

Indomethacin in vivo inhibits the enhancement of the progesterone secretion in response to gonadotrophin-releasing hormone by human corpus luteum. Fulghesu AM, Lanzone A, Di Simone N, Nicoletti MC, Caruso A, Mancuso S. Hum Reprod. 1993;8:35-9.
I.F. 5.506

Human growth hormone enhances progesterone production by human luteal cells in vitro: evidence of a synergistic effect with human chorionic gonadotrophin. Lanzone A, Di Simone N, Castellani R, Fulghesu AM, Caruso A, Mancuso S. Fertil Steril. 1992:92-96.
I.F 5.411

Changes in fatty acids sebum composition during human menstrual cycle: possible relationships with fertile period. Mancuso S, Fulghesu AM, Di Simone N, Riccardi P, Vitale E, Castellani R, Bellante FP, Lanzone A. Acta Eur Fertil.1991;22:42-45.

Effect of opiate receptor blockade on the insulin response to oral glucose load in polycystic ovarian disease. Lanzone A, Fulghesu AM, Fortini A, Cutillo G, Cucinelli F, Di Simone N, Caruso A, Mancuso S. Hum Reprod. 1991;6:1043-9.
I.F. 5.506

Failure of progesterone response to GnRH in hypoprolactinemic women. Caruso A, Fulghesu AM, Di Simone N, Fortini A, Lanzone A, Mancuso S. Infertility 1990;13:181-90.

Effect of gonadotropin-releasing hormone and related analogue on human luteal cells function in vitro. Lanzone A, Panetta V, Di Simone N, Arnò E, Fulghesu AM, Caruso A, Mancuso S. Hum Reprod. 1989;4:906-9.
I.F. 5.506

Effect of human chorionic gonadotropin administration on pitutary and luteal response to gonadotropin-releasing hormone. Lanzone A, Fulghesu AM, Di Simone N, Apa R, Guida C, Caruso A, Mancuso S. Horm Res. 1989;32:203-7.
I.F 2.42

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